Biomolecules detection

Biosensors are devices that have been extensively developed in the last two decades. In fact, the application of MEMS to chemistry and biotechnology has created ion-selective electrodes for blood gases and electrolytes, glucose sensors for diabetes monitoring, amperometric sensors for toxic gases, high temperature diode sensors for determination of gases, and more recently DNA sensors. However, the potential of these sensors is limited since sample preparation step is not integrated to allow the detection of complex biomolecules (i.e. RNA) from raw sample. This proposal sorts out this difficulty by making use of a demonstrated magnetophoresis strategy to be able to detect proteins using Immuno-PCR, RNA using RTPCR or NASBA and DNA using PCR. This level of integration and strategy has never been tried before.

The right balance between relevant, feasible and efficient research.
IKERLAN-IK4, Technological Research Centre. | J.M. Arizmendiarrieta N2 | 20500 Arrasate-Mondragon | Spain | jmruano@ikerlan.es